Saturday, August 30, 2025

Vision-Based Automation in Penetrant Testing #sciencefather #researcherawards #computervision

๐Ÿ” Automating Penetrant Testing with Vision-Based AI

Introduction

Penetrant Testing (PT) is one of the most widely used Non-Destructive Testing (NDT) techniques in industries ranging from aerospace ✈️ to manufacturing ๐Ÿญ. Traditionally, PT relies heavily on manual inspection ๐Ÿ‘€, where operators visually detect flaws after applying penetrants. While effective, this manual approach poses challenges such as inconsistency, subjectivity, and vulnerability to human error ⚠️.

With advancements in artificial intelligence (AI) and computer vision, there is now a significant opportunity to move beyond manual inspection and toward automation ๐Ÿค–. However, fully automated PT systems remain limited due to the absence of reliable evaluation methods.




The Proposed Approach

Our research introduces a vision-based quality evaluation method designed to automate PT by addressing existing limitations:

1️⃣ Detection Network – A deep learning model processes PT images and accurately evaluates penetrant quality.
2️⃣ Preprocessing Network – To overcome poor lighting conditions ๐Ÿ’ก, an image enhancement module improves visual clarity and ensures reliable detection.
3️⃣ Annotated Dataset – We constructed a dedicated dataset with carefully labeled PT images ๐Ÿ—‚️, enabling robust training and experimental validation.

Results and Key Findings

Through rigorous testing, our model achieved remarkable outcomes:

High precision in identifying penetrant quality.
Robust performance even under poor lighting conditions.
Consistent evaluation compared to manual inspections.

These results demonstrate that vision-based automation can significantly enhance PT reliability and efficiency, making it a promising step toward fully automated NDT systems ๐Ÿš€.

Why It Matters

The integration of AI-driven computer vision in PT marks a leap forward for industries that depend on precise flaw detection. Automation not only reduces human error but also improves speed, repeatability, and safety in quality assurance.

By bridging the gap between manual and automated PT, this research paves the way for next-generation inspection systems that will redefine industrial testing and quality control ๐ŸŒ.

Conclusion

The proposed vision-based approach proves that automation in penetrant testing is achievable and reliable. With enhanced accuracy, adaptability, and robustness, AI-powered PT is set to transform Non-Destructive Testing and lead industries toward smarter, safer, and more efficient inspection practices ๐Ÿ”ง✨.

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Monday, August 25, 2025

Pareto Equilibria in Differential Games #sciencefather #researcherawards #ParetoEquilibrium

 

๐ŸŽฎ Differential Games & Pareto Equilibria: A Mathematical Breakthrough

In the fascinating world of game theory ๐Ÿค, researchers often explore how players interact, make decisions, and strive for the best possible outcomes. A recent study dives deep into the mathematics of two-player differential games governed by ordinary differential equations (ODEs) ๐Ÿ“ˆ, shedding light on the nature of Pareto equilibria.

๐Ÿ”‘ Key Insights from the Study

  • The paper establishes that Pareto equilibria in these games form a dense residual subset. This means that such equilibria are not just rare mathematical curiosities—they are fundamentally woven into the structure of the game.

  • Every point of a Pareto equilibrium is shown to be essential ๐ŸŒŸ, meaning small perturbations or adjustments won’t easily disrupt the balance.

  • The research further demonstrates that the set of Pareto equilibria has an essential connected component ๐Ÿ”—, indicating a strong structural stability across solutions.

๐Ÿค” Why Does This Matter?

Pareto efficiency is a cornerstone of economics, decision theory, and control systems. By proving the stability and connectedness of these equilibria in differential games, this work provides new foundations for:

  • Economic modeling ๐Ÿ’ฐ

  • Dynamic optimization in engineering ⚙️

  • Multi-agent systems in AI ๐Ÿค–

๐Ÿš€ Final Thoughts

This study enriches our understanding of equilibrium structures in differential games, offering both theoretical depth and practical potential. The results show that essential equilibria are not only stable but also deeply interconnected, ensuring robustness in complex decision-making scenarios.

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Serial Dilution Improves Prolactin Testing in Pituitary Tumors #sciencefather #researcher #PituitaryTumors

 

๐Ÿงช Prolactin Testing in Pituitary Tumors: Why Serial Dilution Matters

When it comes to diagnosing pituitary tumors, measuring the hormone prolactin (PRL) is a crucial step. Prolactinomas (hormone-secreting tumors) often show very high PRL levels, while non-functioning pituitary adenomas (NFPAs) usually don’t. But here’s the tricky part ๐Ÿ‘‡

Sometimes, patients with large pituitary tumors may show falsely low PRL readings due to something called the “high-dose hook effect”. This happens when extremely high hormone levels overload the test system, leading to misleadingly low results.

๐Ÿ‘‰ The solution? Serial dilution testing, where blood samples are diluted (1:10 or 1:100) before re-measuring PRL.



๐Ÿง  The Study at a Glance

๐Ÿ“ Where: National Institute of Neurosciences, Dhaka
๐Ÿ‘ฅ Who: 73 patients with pituitary macroadenomas
๐Ÿงพ What was done:

  • Clinical features, hormone levels, and imaging were studied.

  • Serum PRL measured before and after dilution.

  • Results compared using statistical agreement (ฮบ statistic).

๐Ÿ” Key Findings

  • Average patient age: 42 years

  • Gender: 28.8% were women

  • Common symptoms: Headache ๐Ÿค• and vision problems ๐Ÿ‘€

  • Tumor size: Average 3.3 cm; about 29% were “giant” tumors ๐Ÿงฉ

๐Ÿ’ก What changed after dilution?

  • 3 patients (4.1%) who looked like they had “low” PRL (<200 ng/mL) actually had much higher levels (>200 ng/mL) after dilution.

  • 7 patients who already showed PRL >200 ng/mL turned out to have very high levels (606–12,582 ng/mL).

  • Statistical analysis showed only moderate agreement between undiluted and diluted PRL results (ฮบ = 0.557).

๐Ÿฅ Why This Matters

Without serial dilution, some patients may be misdiagnosed as having a non-functioning tumor instead of a prolactinoma. This could affect their treatment plan ๐ŸŽฏ. The study highlights that even with modern hormone tests, the hook effect remains a real issue.

✔️ Routine dilution testing in patients with large pituitary adenomas can make diagnosis more accurate, avoid confusion, and guide better treatment decisions.

๐Ÿ“Œ Takeaway

  • ๐Ÿ”ฌ Hook effect = false low prolactin readings in big tumors

  • ๐Ÿ’‰ Serial dilution = clearer diagnosis

  • ๐Ÿง  Better diagnosis = better patient care

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Friday, August 22, 2025

AACR Project GENIE Biopharma Collaborative #sciencefather #researcher #AACR

 

๐Ÿ”ฌ AACR Project GENIE Biopharma Collaborative: Advancing Cancer Research with Real-World Data

Cancer research is entering a new era—one powered by large-scale collaboration, cutting-edge genomics, and real-world evidence. ๐ŸŒ✨ At the heart of this transformation is the American Association for Cancer Research (AACR) Project GENIE Biopharma Collaborative (BPC), a groundbreaking partnership between 10 leading biopharma companies and GENIE-participating academic institutions.




๐Ÿงฌ What is the GENIE BPC?

The BPC is a multi-phase, pre-competitive collaboration focused on building deeply annotated patient cohorts within the GENIE Registry. The effort spans 10 major solid tumors and integrates:

  • ๐Ÿ‘ฉ‍⚕️ Patient demographics

  • ๐Ÿฉบ Clinical diagnoses

  • ๐Ÿงช Genomic data

  • ๐Ÿ’Š Treatment histories

  • ๐Ÿ“Š Longitudinal, real-world outcomes

This structured data framework ensures interoperability, accuracy, and compatibility with other models—setting a new standard for collaborative cancer research.

๐Ÿ”Ž Why is this Important?

Before being publicly released, each dataset undergoes rigorous quality control ✅ across multiple institutions, ensuring:

  • ๐Ÿ”„ Consistency of data

  • ๐ŸŽฏ Accuracy of clinical and genomic information

  • ๐Ÿ”’ Reliability for research and decision-making

This makes the BPC a trusted resource for both academia and industry.

๐Ÿ’ก Key Insights from Early Analyses

Already, the BPC has delivered impactful discoveries, including:

  • ๐Ÿ”“ Validation of resistance mutations caused by cancer treatments

  • ๐Ÿงญ Genomic drivers linked to metastatic sites

  • ๐Ÿ“ˆ Real-world response data that closely match clinical trial results

These findings highlight the power of real-world evidence (RWE) to complement traditional clinical studies.

๐Ÿค Collaboration in Action

The BPC thrives on centralized management and a shared knowledgebase that connects diverse teams—academic researchers, clinicians, and biopharma scientists—all working toward a common goal: improving patient outcomes.

๐Ÿš€ Looking Ahead

The future of the BPC is even more exciting:

  • ⚙️ Automation will streamline clinical annotation, enabling data collection at scale.

  • ๐Ÿ” Increased granularity will enhance insights into patient care.

  • ๐ŸŒ Expanded cohorts will cover more cancer types, broadening impact across oncology.

๐ŸŒŸ Conclusion

The AACR Project GENIE BPC is more than just a data-sharing initiative—it’s a transformative engine of discovery in precision oncology. By bridging the gap between clinical trials and real-world outcomes, it is shaping a future where cancer treatment is smarter, faster, and more personalized. ๐Ÿ’ก๐Ÿ’ช

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Thursday, August 21, 2025

Gut–X Axes: The Hidden Link Between Your Gut and Type 2 Diabetes #sciencefather #researcher #Type2Diabetes

 

๐Ÿฆ  Gut–X Axes: The Hidden Link Between Your Gut and Type 2 Diabetes

Type 2 diabetes (T2D) is often seen as a condition of the pancreas and insulin resistance ๐Ÿ’‰๐Ÿฌ, but research in the last decade has revealed a surprising player at the center of this disease — the gut ๐Ÿฆ .

Far from being just a digestive organ, the gut hosts trillions of microbes and specialized enteroendocrine cells that send signals to almost every part of the body. When this delicate balance is disturbed — a state called dysbiosis ⚖️ — it can trigger inflammation, obesity, insulin resistance, and even ฮฒ-cell dysfunction.

This gut-centered communication happens through what scientists now call the “Gut–X axes”, where the gut interacts with multiple organs and systems that influence T2D development. Let’s explore these fascinating connections.


๐Ÿ”ฌ The Gut–Pancreas Axis

The gut produces hormones like GLP-1 and GIP (incretins) that directly affect how much insulin and glucagon the pancreas releases.

  • Healthy gut microbes → boost incretins, support insulin secretion.

  • Dysbiosis → weak incretin response, damaged ฮฒ-cells.

๐Ÿ‘‰ This is why GLP-1 based therapies (like semaglutide) have become a game-changer in diabetes management.

๐Ÿฝ️ The Gut–Endocrine Axis

Your gut talks to the endocrine system through hormones like PYY and ghrelin, influencing appetite, fat storage, and energy balance.

  • PYY = “I’m full” hormone ๐Ÿ˜‹

  • Ghrelin = “I’m hungry” hormone ๐Ÿ˜ซ

Neural pathways link these signals with the brain and adipose tissue, showing how the gut directly shapes metabolism and body weight.

๐Ÿซ€ The Gut–Liver Axis

Gut microbes also modify bile acids ๐Ÿงช, which activate receptors like FXR and TGR5 in the liver. These pathways regulate:

  • ๐Ÿงˆ Fat metabolism

  • ๐Ÿซ€ Insulin sensitivity

  • ๐Ÿ›ก️ Inflammation

But when gut permeability increases, bacterial endotoxins (LPS) leak into circulation → fueling non-alcoholic fatty liver disease (NAFLD) and worsening insulin resistance.

๐Ÿฉธ The Gut–Kidney Axis

Your kidneys aren’t spared either! The gut influences nutrient handling and generates uremic toxins that contribute to diabetic kidney disease (DKD).

  • ๐Ÿ’Š Therapies like SGLT2 inhibitors and incretin-based drugs partly work through this gut–kidney cross-talk, protecting kidney health while improving glucose control.

๐ŸŒ Shared Mechanisms Across Axes

Despite the complexity, some common molecular players appear in all Gut–X axes:

  • ๐Ÿฅฆ Short-chain fatty acids (SCFAs) → improve insulin sensitivity

  • ๐Ÿ”ฅ Lipopolysaccharides (LPS) → drive chronic inflammation via TLR4

  • ๐ŸŒฟ Aryl hydrocarbon receptor (AhR) ligands → fine-tune immunity

Together, they form a unified model of how gut-derived signals orchestrate multi-organ dysfunction in T2D.

๐Ÿ’ก Clinical Implications & Future Directions

Targeting the gut and its microbiota opens up exciting possibilities:

  • ๐Ÿฅ— Diet and prebiotics

  • ๐Ÿ’Š Microbiome-based drugs

  • ๐Ÿ’‰ Next-gen incretin therapies

But — ⚠️ most findings come from animal studies or small human trials. More large-scale clinical research is needed before these therapies become mainstream.

✨ Takeaway

Your gut is more than a digestive machine — it’s a control hub for metabolism, immunity, and hormone regulation. By understanding the Gut–X axes, researchers are uncovering new pathways to treat and even prevent Type 2 diabetes.

The future of T2D therapy might not just be about insulin or glucose — it may lie in modulating the gut itself ๐ŸŒฑ๐Ÿฆ .

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Multimodal Framework for Efficient Cancer Survival Prediction #sciencefather #researcher #AIMedicine

 

๐Ÿ”ฌ Multimodal Framework for Efficient Cancer Survival Prediction

Cancer survival prediction is one of the most critical challenges in healthcare ๐Ÿฅ. Accurate estimation not only supports better medical decision-making but also empowers doctors to deliver personalized treatment plans ๐ŸŽฏ. By identifying high-risk patients early, healthcare providers can ensure timely interventions, leading to improved treatment outcomes ๐Ÿ’ก.

๐ŸŒ The Challenge

Traditional methods often rely on single-modality data (either images or genetic information) ❗. While useful, these approaches miss the bigger picture, and many models suffer from excessive computational complexity ⏳—limiting their real-world use in large-scale medical datasets.

๐Ÿ’ก Our Solution

To overcome these hurdles, we propose a novel multimodal survival prediction framework that combines Whole Slide Images (WSI) ๐Ÿ–ผ️ with genomic data ๐Ÿงฌ.

✨ Key Innovations:

  • Attention Mechanisms ๐Ÿ”Ž – Capture complex correlations within and across both modalities.

  • Locality-Sensitive Hashing ⚡ – Optimizes self-attention, significantly cutting down computational costs.

  • Scalability ๐Ÿ“ˆ – Efficiently processes large, high-resolution datasets for practical clinical use.

๐Ÿ“Š Results

Experiments on the TCGA-BLCA dataset confirm that integrating WSI and genomic data outperforms unimodal methods ๐Ÿš€. The optimized attention mechanism ensures high predictive accuracy while being resource-efficient—making it highly suitable for large-scale applications.

✅ Conclusion

Our framework offers a robust, scalable, and efficient solution for cancer survival prediction. By leveraging multimodal integration and optimized attention, this approach paves the way for AI-powered clinical decision support systems ๐Ÿง‘‍⚕️๐Ÿค–, transforming the future of precision medicine.

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Tuesday, August 19, 2025

Satellites Predict Extreme Weather #sciencefather #researcher #satellitedata

 

๐ŸŒง️ Understanding Extreme Rainfall: Lessons from Medicane Daniel and Satellite Precipitation Data

๐ŸŒ Introduction

Accurately estimating rainfall is critical for predicting and mitigating the impacts of extreme weather events, particularly in regions vulnerable to Mediterranean cyclones (Medicanes). One such event, Medicane Daniel, struck Central Greece in September 2023, causing devastating floods across the Thessaly Plain. This study investigates how advanced satellite-based precipitation products, specifically the Integrated Multi-Satellite Retrievals for GPM (IMERG), can be combined with ground-based observations to improve accuracy in rainfall monitoring.


๐Ÿ›ฐ️ What is IMERG and Why Does It Matter?

The IMERG system, developed under NASA’s Global Precipitation Measurement (GPM) mission, integrates multiple satellite observations to estimate global rainfall in near real time. During extreme weather, such as tropical storms, cyclones, or monsoon floods, having timely and reliable rainfall data is vital for:

  • Disaster preparedness – giving authorities early warning for evacuation.

  • Agricultural resilience – helping farmers anticipate crop damage.

  • Urban planning – enabling better flood control and water management.

Example: In India’s 2018 Kerala floods, satellite rainfall estimates supported quick decision-making when ground stations were damaged by rising waters.

๐Ÿ“Š How the Study Was Conducted

To evaluate IMERG’s accuracy during Medicane Daniel, three versions were tested:

  • Final Run (FR) – highest-quality dataset after all calibrations.

  • Early Run (ER) – quick estimates available soon after the event.

  • Late Run (LR) – improved accuracy but still intermediate.

These were compared with ground-based rain gauge data, interpolated using two spatial methods:

  • Inverse Distance Weighting (IDW)

  • Ordinary Kriging

Statistical indicators such as the Probability of Detection (POD), False Alarm Ratio (FAR), Critical Success Index (CSI), and Peirce Skill Score (PSS) were used to verify performance.

๐Ÿ”Ž lKey Findings

  • The Final Run (FR) product showed the highest agreement with ground data, reaching a correlation (R) of 0.87 and CSI up to 0.995 at 100 mm thresholds.

  • Kriging outperformed IDW in spatial accuracy, achieving an almost perfect correlation (R = 0.99).

  • Combining satellite and ground-based data provided more localized, precise rainfall estimates, particularly useful in complex terrains like Thessaly.

Example: Similar approaches are used in California’s Sierra Nevada region, where blending satellite snowpack data with ground sensors improves water resource management.

๐ŸŒฑ Why Does This Research Matter?

Accurate rainfall monitoring is not just about science—it directly affects communities and ecosystems. By improving rainfall estimates:

  • Emergency response teams can deploy resources more effectively.

  • Hydrologists can better model flood risks.

  • Farmers can plan irrigation and crop cycles during extreme drought or rainfall events.

Example: In Bangladesh, integrating satellite rainfall data with river gauge networks has improved flood forecasting, saving thousands of lives annually.

๐Ÿš€ Looking Ahead

This study highlights the importance of combining satellite precipitation data with ground observations through advanced spatial methods like kriging. As climate change intensifies storms, adopting such approaches will enhance resilience in vulnerable regions.

  • Kriging offers superior spatial accuracy for detailed hydrological modeling.

  • IMERG-FR provides a reliable quick-response tool during emergencies.

Ultimately, blending these methods can become a gold standard for disaster preparedness worldwide.

Conclusion

The case of Medicane Daniel illustrates how technology, when paired with local data, can transform how we understand and respond to extreme weather events. As climate change continues to amplify storms, investing in satellite-ground hybrid monitoring systems will be essential to safeguard communities, agriculture, and infrastructure.


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Cystic Ovarian Disease in Dairy Cows #sciencefather #researcher #animalhealth

 

Cystic Ovarian Disease in Dairy Cows: How Lipid Metabolism and Steroidogenesis Disrupt Fertility

Cystic ovarian disease (COD) is one of the most frequent reproductive disorders in dairy cattle, responsible for significant economic losses due to extended calving intervals, reduced conception rates, and subfertility. COD is defined by the persistence of ovarian follicles that fail to ovulate and instead undergo abnormal growth and hormonal imbalance.

A recent study explored the intricate molecular changes in lipid metabolism, ketone body regulation, and steroidogenesis that occur within ovarian follicular cells during COD and experimentally induced follicular persistence.



๐Ÿ”ฌ Study Overview

  • Objective: To analyze the expression of key receptors and enzymes linked to cholesterol transport, ketone body metabolism, and steroid hormone synthesis in ovarian follicles.

  • Model:

    • Dairy cows with induced follicular persistence (via prolonged progesterone exposure).

    • Dairy cows diagnosed with spontaneous COD.

  • Methods:

    • Immunohistochemistry to evaluate protein levels of enzymes and receptors:

      • Cholesterol & lipid metabolism: HMG-CoA reductase, mitochondrial HMG-CoA synthase (mHMG-CoA synthase), SCOT, LDL-R, SRB-1.

      • Steroidogenesis: CYP17A1, CYP19A1, StAR, 3ฮฒHSD.

    • Biochemical analysis of follicular fluid and plasma: total cholesterol, HDL, LDL, and ฮฒ-hydroxybutyrate (BHB).

๐Ÿ“Š Key Findings

  1. Cholesterol Transport Receptors Altered

    • SRB-1 and LDL-R protein levels were higher in granulosa cells from cows in late stages of follicular persistence and in COD cows compared to healthy controls.

  2. Ketone Body Enzymes Suppressed

    • mHMG-CoA synthase, HMG-CoA reductase, and SCOT showed the opposite trend, with lower expression in COD and late persistence groups.

  3. Steroidogenesis Imbalance

    • CYP19A1 (aromatase, critical for estrogen production) was lower in early persistent follicles (5 days).

    • 3ฮฒHSD (enzyme for progesterone and androgen synthesis) was higher in late persistent stages compared to controls.

  4. Biochemical Profiles

    • Follicular fluid cholesterol dynamics were altered, suggesting disrupted lipid handling in the ovarian environment.

๐Ÿงฉ What Do These Results Mean?

These findings highlight that COD in dairy cows is not just a hormonal disorder but also a metabolic one.

  • Upregulation of cholesterol transporters (SRB-1, LDL-R) suggests the follicle attempts to increase cholesterol availability, potentially fueling abnormal steroid production.

  • Downregulation of ketone body enzymes points to reduced energy metabolism within follicular cells, possibly compromising normal follicle function.

  • Imbalances in CYP19A1 and 3ฮฒHSD indicate disrupted estrogen and progesterone pathways, which contribute to failure of ovulation and cyst formation.

Ultimately, these metabolic-steroidogenic alterations in persistent follicles may lock the ovary into a dysfunctional state, perpetuating subfertility in affected cows.

๐Ÿ„ Implications for Dairy Herd Management

Understanding the molecular underpinnings of COD opens new opportunities:

  • Diagnostic biomarkers: SRB-1, LDL-R, and steroidogenic enzyme levels may serve as early indicators of follicular dysfunction.

  • Therapeutic targets: Strategies aimed at restoring metabolic balance in granulosa cells could help prevent or manage COD.

  • Nutritional interventions: Since ketone body metabolism and cholesterol handling are involved, dietary management may play a role in reducing COD incidence.

๐ŸŒฑ Conclusion

This study provides compelling evidence that metabolic disruptions in cholesterol and ketone body pathways intertwine with steroidogenesis defects to drive cystic ovarian disease in dairy cows. Addressing COD requires a holistic approach that considers not only hormonal therapies but also metabolic health and nutrition of the herd.

By shedding light on these molecular changes, researchers pave the way for improved reproductive management strategies in dairy production, ultimately enhancing both animal welfare and farm profitability.

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Sunday, August 17, 2025

AI Uncovers Hidden Alloy Power #sciencefather #researcher #materialscience

 

๐ŸŒŸ Predicting Grain-Boundary Segregation with Machine Learning

Grain-boundary (GB) segregation of solute elements plays a crucial role in determining the properties of alloys ⚙️. From phase transformations ๐Ÿ”„ to mechanical strength ๐Ÿ’ช and even the stability of nanocrystalline structures ๐Ÿ”ฌ—this process lies at the heart of materials design.

Traditionally, density functional theory (DFT) ๐Ÿงฎ has been the go-to tool for calculating the site-specific segregation energies. While highly accurate, DFT is also computationally expensive ⏳, limiting its use for exploring a wide range of solute elements and alloy systems.

๐Ÿ‘‰ Enter machine learning (ML) ๐Ÿค–. By training ML models on DFT-generated data, researchers can now predict segregation energies faster and more efficiently.




๐Ÿ”‘ Our Approach

  • We combined structural descriptors of segregation sites ๐Ÿ—️ with element-specific parameters of solutes ๐Ÿงช.

  • We applied cross-validation ✅ and extrapolation scores ๐Ÿ“Š to identify the best-performing descriptor sets.

  • The optimized ML model can then predict segregation energies for solutes not included in the original dataset ๐Ÿš€.

๐Ÿงฉ Application to Tungsten (W)

We tested this approach on the segregation of transition metals in tungsten (W). Results showed:

  • Excellent accuracy ๐ŸŽฏ compared to DFT and literature values.

  • Robust predictions for elements outside the training set.

๐Ÿ“‚ Open Science Contribution

To support further research, we’ve made our codes and datasets publicly available ๐Ÿ’ป๐Ÿ“ฆ, enabling others to apply and extend our model.

✨ Why This Matters?

This ML-driven approach accelerates the design of advanced alloys ๐Ÿ”ง, supporting innovations in energy, aerospace, and nanotechnology ๐ŸŒ. By lowering computational barriers, we open the door to faster discoveries and smarter materials engineering.

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Thursday, August 14, 2025

A Research on Machine Learning Methods and Its Applications #sciencefather #researcher #ML

 

๐Ÿš€ The Journey of Machine Learning: From the 1950s to Today

Machine Learning (ML) ๐Ÿค– is a fascinating branch of Artificial Intelligence (AI) ๐Ÿง  that first emerged in the 1950s. While the early steps in this field were promising, there were no major breakthroughs for decades.

However, in the 1990s, researchers reignited their interest ๐Ÿ”ฅ in machine learning, leading to rapid progress that has brought us to where we are today.

๐Ÿ“œ A Brief History of Machine Learning

  • 1950s: Birth of ML as a subfield of AI

  • Long pause: Limited research activity for several decades

  • 1990s: Revival of research and the start of modern ML development

  • Today: Widespread applications and fast-evolving technologies

๐Ÿ“ˆ Why Machine Learning is Growing So Fast

The explosive growth of data ๐Ÿ“Š in recent decades has been a key driver for ML.
Analyzing and processing massive datasets is a complex challenge ๐Ÿงฉ—one that machine learning is uniquely suited to solve.

ML works on the principle of:

๐Ÿง Learning from past data to create models that make accurate predictions for new data.

The more data we have, the better the models become.

๐Ÿ›  Methods & Applications of Machine Learning

Methods include:

  • ๐Ÿ“ Supervised Learning

  • ๐Ÿงฉ Unsupervised Learning

  • ๐Ÿ”„ Reinforcement Learning

Applications span across:

  • ๐Ÿ“ท Image & Video Recognition

  • ๐Ÿ’ฌ Natural Language Processing

  • ๐Ÿš— Autonomous Vehicles

  • ๐Ÿ’น Financial Forecasting

  • ๐Ÿฅ Medical Diagnostics

๐Ÿ”ฎ The Future of Machine Learning

As data keeps growing ๐Ÿ“ก, machine learning research will continue to advance in parallel.
We can expect smarter algorithms, faster computation, and more impactful real-world solutions in the years ahead.


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Tuesday, August 12, 2025

Unveiling the Truth About Stablecoins in Crypto Market #sciencefather #researcher #cryptomarket

 

Can Stablecoins Truly Anchor the Volatile Crypto Market?

In the fast-changing ๐ŸŒช️ world of cryptocurrencies, the idea of using stablecoins as market anchors has gained huge attention. But are they truly stable, independent, and resilient enough to play this role? This study dives deep into that question using an innovative, three-dimensional framework.



๐Ÿ“Œ Purpose of the Study

This research empirically examines the potential of stablecoins to act as anchors in the volatile cryptocurrency market. The framework evaluates them on three key dimensions:
1️⃣ Stability – How much they maintain value consistency.
2️⃣ Independence – How free they are from the influence of other assets.
3️⃣ Resilience – How well they withstand and recover from market shocks.

๐Ÿ’ฑ Assets Analyzed

The study compares:

  • Stablecoins: Tether (USDT), USD Coin (USDC), Binance USD (BUSD)

  • Top Unpegged Cryptos: Bitcoin (BTC), Ethereum (ETH), Binance Coin (BNB)

  • Major Fiat Currencies (after USD): Euro (EUR), Japanese Yen (JPY), British Pound (GBP) – all USD-denominated ๐Ÿ’ต

๐Ÿ› ️ Methodology

To assess stability, independence, and resilience, three advanced methods were used:
๐Ÿ”น Granger Causality – Tests predictive relationships between assets.
๐Ÿ”น ADCC-GARCH (Asymmetric Dynamic Conditional Correlation) – Measures volatility spillover and correlations ๐Ÿ“ˆ.
๐Ÿ”น Transfer Entropy – Captures nonlinear relationships and information flows.

For resilience, market liquidity was measured using:
๐Ÿ’ง Turnover Ratio weighted by Market Cap
๐Ÿ“š Abdi & Ranaldo (2017) Method

๐Ÿ“Š Key Findings

❌ Stablecoins are not consistently more stable, independent, or resilient than other assets.
⚠️ Significant volatility spillovers exist between stablecoins, unpegged cryptos, and fiat currencies.
๐Ÿค” The idea that stablecoins could become a reliable private alternative to fiat currency is questionable.

๐Ÿ“ข Implications

These findings challenge the perception of stablecoins as safe havens in crypto markets. While they can reduce volatility in certain contexts, their vulnerability to broader market dynamics limits their role as robust anchors.

๐Ÿ Conclusion

Stablecoins may not yet be the financial lifeboats ๐ŸŒŠ many hoped for. To serve as true anchors, they must demonstrate greater independence from crypto volatility, higher liquidity resilience, and consistent stability in diverse market conditions.


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Smart Framework for Choosing Reliable Hydrogen Energy Suppliers #sciencefather #researcher #hydrogenenergy

 

⚡๐Ÿ”‹ Choosing the Right Hydrogen Energy Supplier: A Smarter Way Forward ๐ŸŒ๐Ÿ’ก

In the race toward a greener future, hydrogen energy is emerging as a game-changer for clean, sustainable power. But with its growing demand, choosing a trustworthy hydrogen energy supplier isn’t as simple as picking the lowest price. ๐ŸŒฑ⚖️ Navigating economic viability ๐Ÿ’ต and energy security ๐Ÿ”’ is key to ensuring long-term success.




This innovative research presents a decision-making framework that blends:

  • ๐Ÿ“ˆ GARCH Model (Generalized Autoregressive Conditional Heteroscedasticity): Captures and analyzes price volatility in hydrogen markets.

  • ๐Ÿค– Fuzzy TOPSIS (Technique for Order Preference by Similarity to Ideal Solution): Handles uncertainty in multi-criteria supplier evaluation.

  • ๐Ÿ“Š Soft Analytic Hierarchy Process (AHP): Determines selection criteria weights for more balanced decision-making.

๐Ÿ“ Case Study: China (2015–2023) ๐Ÿ‡จ๐Ÿ‡ณ

Using real-world data, this framework was tested to optimize hydrogen procurement. The results showed that it:
✅ Promotes economic sustainability
✅ Strengthens energy security
✅ Ensures affordable hydrogen supply chains

๐Ÿ’ก Why It Matters

By improving supplier selection, this method supports sustainable hydrogen-based energy systems — reducing risks, improving cost efficiency, and accelerating the global clean energy transition. ๐ŸŒ๐Ÿ’š

๐Ÿš€ The future of hydrogen energy isn’t just about production — it’s about making the right choices in procurement. With tools like GARCH + Fuzzy TOPSIS + Soft AHP, decision-makers can confidently build resilient and sustainable energy networks.

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Sunday, August 10, 2025

Revolutionizing CMOS Sensors with Smart ADC #sciencefather #researcher #cmos

 

๐Ÿ“ธ Smarter, Quieter, and More Efficient: Interval-Adaptive CMS ADC for CMOS Image Sensors

In the world of CMOS Image Sensors (CIS), achieving crystal-clear images often comes down to one big challenge — reducing readout noise ๐ŸŽฏ. Correlated Multiple Sampling (CMS) has long been the go-to method for this, but it comes with a trade-off: longer conversion times ⏳ and higher power consumption ⚡ in the ADC.

This research introduces a game-changing solution — an Interval-Adaptive Correlated Multiple Sampling ADC with Prejudgment Logic ๐Ÿค–. Here’s how it works:

1️⃣ Two-Step Smart Conversion

  • Step 1: A 6-bit SAR ADC does a coarse conversion to quickly select a small-range interval.

  • Step 2: Another 6-bit fine conversion is performed only in that interval for higher accuracy.

2️⃣ Power-Saving Prejudgment Logic

  • By recognizing that neighboring pixels often have similar values ๐Ÿ–ผ️, the system can skip the coarse step entirely in many cases.

  • The trick? Two columns share one SAR ADC, making this possible without extra hardware overhead.

๐Ÿ›  Fabrication & Performance

  • Process: 130 nm CIS

  • DNL: –0.75 / +1 LSB ๐Ÿ“

  • INL: –1.2 / +0.5 LSB ๐Ÿ“

  • Input-Referred Noise: 122.5 ยตVrms ๐Ÿ”‡

  • Conversion Time: Faster in bright conditions ☀️, adaptive in dark conditions ๐ŸŒ™

  • Power Savings: Up to 20.3% less column power compared to traditional CMS ADC ⚡✅

๐Ÿ’ก Why it matters: This approach delivers low-noise imaging, shorter readout times, and significant power savings — making it ideal for high-performance cameras, mobile devices ๐Ÿ“ฑ, and machine vision systems ๐Ÿค–.

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A methodology for the integration of fire risk in building life cycle analysis #sciencefather #researcherawards #fire

  Integrating Fire Risk into Building Life Cycle Analysis Understanding fire risk is essential for creating safer, more resilient, and sust...