Advancing Aquaculture Health: Dual-Adjuvant Vaccine Strengthens Immunity in Nile Tilapia #sciencefather #researcheraward #fish

🧫🐟 Boosting Fish Immunity: A New Vaccine Strategy for Sustainable Aquaculture 🌊

Aquaculture is a lifeline for millions, ensuring food security and supporting economies, particularly in low- to middle-income countries. Yet, the sector is under pressure from recurring fish diseases and rising antibiotic resistance. One major pathogen, Edwardsiella tarda, poses a global threat to aquaculture, especially in Nile tilapia (Oreochromis niloticus), a commercially vital species.

💉 To reduce antibiotic dependence, scientists have formulated an innovative formalin-killed vaccine (FKV) fortified with IFN-γ and β-glucan as immune-enhancing adjuvants. The virulent E. tarda strain was cultured, inactivated using 0.5% formalin, and blended with these adjuvants to enhance immunogenicity and ensure safe protection.

🐠 Upon vaccination, Nile tilapia exhibited robust immune responses and improved resistance to E. tarda infection. 

Key findings included:
✨ Elevated antibody (IgM) levels at 14 and 28 days post-vaccination.
⚡ Enhanced enzyme activities—SOD, MPO, LZM, and bactericidal function—indicating a strong innate immune response.

🧬 Upregulated immune gene expression (IgM, TCR β, and MHC II), signifying heightened adaptive immunity.

🔬 After a pathogen challenge, vaccinated fish showed significantly higher survival rates, confirming the vaccine’s protective efficiency. This dual-adjuvant approach successfully stimulates both humoral and cellular immunity, ensuring longer-lasting protection.

🌱 Overall, this research presents a sustainable, antibiotic-free vaccination strategy for aquaculture. By strengthening disease resistance and promoting fish health, it supports the development of eco-friendly aquaculture systems that balance productivity with environmental safety.

Scientific World Research Awards🏆

Visit our page : https://scientificworld.net/

Nominations page📃 : https://scientificworld.net/award-nomination/?ecategory=Awards&rcategory=Awardee

Get Connects Here:
==================

Youtube: https://www.youtube.com/@Scientificresearch-04

Instagram : https://www.instagram.com/swr_awards/

Blogger :https://www.blogger.com/blog/posts/8295489504259175195?hl=en&tab=jj

Twitter :https://x.com/SWR_Awards

What'sApp: https://whatsapp.com/channel/0029Vb5WOsUH5JLpZ1w0RD2M